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|Other Name:||Bromoaceticacid Tert-butyl Ester||Cas No.:||5292-43-3|
|Purity (%) (GC):||99.0 Min||Appearance:||Colorless Transparent Liquid|
|Moisture (%):||0.1 Max||Acid Number Mg KOH/g:||0.1max|
|Relative Density (20/20℃):||1.205-1.210||Refractive Index At 20℃:||1.444-1.446|
Tert-butyl bromoacetate is used to synthesiz amino acids and peptides compound.
It's a common alkylating agent. Used to synthesize collagenase inhibitors (S,S,R)-(-)- actinonin. To replace butyl as the study object.
Formula structure of Tert-butyl bromoacetate:
|Chemical Name||Tert-butyl bromoacetate|
1-Butylbromoacetate; Acetic acid, bromo-, tert-butyl ester; aceticacid,bromo-,1,1-dimethylethylester; BrCH2C(O)OC(CH3)3; 2-BROMOACETIC ACID-TERT-BUTYL ESTER; BROMOACETIC ACID TERT-BUTYL ESTER; BUTYLBROMOACETATE-TERT; TERT-BUTYL 2-BROMOACETATE
Physical property of Tert-butyl bromoacetate:
|Appearance||Colorless transparent liquid|
|Purity (%) (GC)||99.0 min|
|Relative Density (20/20℃)||1.205-1.210|
|Refractive index at 20℃||1.444-1.446|
|Moisture (%)||0.1 max|
|Acid Number mg KOH/g||0.1max|
Chemical properties of Tert-butyl bromoacetate
It burns easily with open fire. Burning and decomposition by high heat produces toxic gases.
Combustion decomposition products are carbon monoxide, carbon dioxide, hydrogen bromide.
Risk profile/editing by tert-butyl bromoacetate
Flammable liquids (category 3)
Aldrich-124230 page 2 of 9
Skin irritation (category 2)
Eye irritation (category 2A)
Specific target organ systemic toxicity (single exposure) (category 3)
GHS label elements, including prophylactic statements
H226 flammable liquids and vapors
H315 causes skin irritation.
H319 causes severe eye irritation.
H335 may cause respiratory irritation.
The prevention of
P210 stays away from heat, sparks, open flame and hot surfaces. - no smoking.
P233 keeps the container closed.
The P240 container and receiving equipment are grounded/equipotential connected.
P241 USES explosion-proof electrical/ventilation/lighting equipment.
P242 can only use tools that do not generate sparks.
P243 adopts measures to prevent electrostatic discharge.
P261 avoid inhaling dust/smoke/gas/smoke/steam/spray.
Clean the skin thoroughly after P264 operation.
P271 can only be used outdoors or in a well-ventilated area.
P280 wear protective gloves/protective clothing/goggles/masks.
P303 + P361 + P353 such as skin (or hair) contamination: remove/remove all contaminated clothing immediately. Wash your skin with water
If inhaled, move the patient to fresh air and rest in a good breathing posture.
If contact with eyes, rinse slowly and gently with water for a few minutes. If wear contact lens and can conveniently take
Get out, remove the contact lens, and continue to rinse.
P312 if feeling unwell, call for help poison control center or doctor.
P321 specific treatment (see first aid instructions provided on this label).
If skin irritation occurs, seek medical treatment.
P337 + P313 if still feeling eye irritation: see a doctor/see a doctor. If you still feel eye irritation, seek medical treatment.
P362 remove any contaminated clothes and wash them before reuse.
P370 + P378 fire: extinguish fire with dry sand, dry chemicals or alcohol-resistant foam.
P403 + P233 stored in a well-ventilated place. Keep the container closed.
P403 + P235 are stored in a well-ventilated place. Keep it cold.
P405 storage place should be locked.
To deal with
P501 treatment of contents/containers to approved waste treatment plants.
Packing and storage of Tert-butyl bromoacetate:
200L (250kgs) plastic pail net or instructed by the customer. Storage at room temperature stable, in closed containers in normal storage and treatment conditions.
At least 2 years when stored in sealed packing under above mentioned conditions.